What It’s Used For

  • Saxenda is prescribed for chronic weight management in patients with obesity or overweight (BMI criteria apply).
  • It is used alongside a reduced-calorie diet and increased physical activity.
  • It may also be recommended for patients with weight-related health conditions, such as type 2 diabetes, high blood pressure, or high cholesterol.

How It Works

  • Saxenda is a GLP-1 receptor agonist, similar to Ozempic (approved for diabetes management), but specifically approved for weight management.
  • It helps regulate appetite by acting on brain receptors that control hunger, leading to reduced calorie intake.
  • It also slows stomach emptying, helping patients feel full for longer.

How It’s Taken

  • Saxenda is a daily subcutaneous injection, administered at the same time each day.
  • The injection is given in the abdomen, thigh, or upper arm.
  • Dosing starts low and is gradually, 0.6 mg, and increased over several weeks to the target dose (3.0 mg daily) to minimize side effects.

Potential Side Effects

  • Common side effects: Nausea, vomiting, diarrhea, constipation, headache, and stomach discomfort. These typically improve as the body adjusts to the medication.
  • Serious side effects: Risk of pancreatitis, gallbladder problems (e.g., gallstones), thyroid tumors (rare), and kidney issues.
  • Low blood sugar: This is more likely in people using Saxenda with other diabetes medications.
  • Contact your healthcare provider if you experience severe side effects like abdominal pain, swelling in the neck, or symptoms of dehydration.

Precautions and Lifestyle Tips

  • Medical history: Inform your doctor if you have a personal or family history of thyroid cancer, pancreatitis, or gallbladder issues.
  • Lifestyle changes: Saxenda is most effective when paired with a healthy diet and regular physical activity.
  • Missed doses: If a dose is missed, resume the usual schedule. Do not double doses.
  • Monitoring: Regular follow-ups with your doctor are essential to assess progress, adjust dosage, and monitor for side effects.
  • Drug interactions: Inform your doctor about any other medications, supplements, or herbs you’re taking to avoid potential interactions.